HOME > Hospital search > Keio University Hospital Tumor Center

Keio University Hospital Tumor Center

Conditions Treated
Early-Stage Gastrointestinal Cancer (Esophageal Cancer, Stomach Cancer, Duodenal Cancer, Colorectal [Large Intestinal] Cancer).

Treatment Methods (Endoscopic Surgery/Laparoscopic Surgery of Early-Stage Gastrointestinal Cancer, Stomach Cancer Reductive Surgery with Sentinel Lymph Node Biopsy)

The main treatment for gastrointestinal cancer is surgical resection. However, resection of a large area can greatly influence the daily life of the patient afterward. Organs should be retained wherever possible to prevent degradation of QOL. Endoscopic submucosal dissection (ESD), performed for early-stage cancers that have not metastasized to the lymph nodes, can cure a cancer completely: an endoscope is used to resect only the tumor, with the organs retained.

After healing, the patient can return to normal life with nearly 100% probability. If the cancer is early stage but has advanced somewhat, or if there is a possibility of it spreading to the lymph nodes, then surgery using a laparoscope in cooperation with the surgery department is possible, which is far less invasive than gastrectomy in laparotomy. Our center has great experience and sophisticated technology with both of these methods, so we can provide seamless medical treatment.

Today, the latest low-invasive medical treatment is reductive surgery based on sentinel lymph node biopsy. In gastrectomy, a somewhat larger area is usually resected due to the risk of the cancer spreading (metastasis). In contrast, sentinel lymph node biopsy reveals whether any cancer has metastasized, and if not, the organ can be retained. We use an endoscope to inject an isotope or coloring agent in the vicinity of the lesion, then use a laparoscope to search for any lymph node from which the isotope or coloring agent oozes out, and ablate (eliminate) it.

Finally, we use a microscope to verify if the cancer has metastasized. If not, we perform a reductive surgery with the minimum area of resection, but if it has metastasized, we perform a general stomach cancer surgery, called gastrectomy or total lymph node dissection. Because we perform a rapid diagnosis during surgery to assess any metastasis, a definite diagnosis and surgery are performed at the same time, which is less invasive for the patient. This treatment method has already proven effective for breast cancer and malignant melanoma, but our medical team was the world’s first to apply it to gastrointestinal cancer and report the results. Thus, we have world-leading experience in this field.

Disorders such as cerebral infarction, myocardial infarction, angina, dialysis, or chronic hepatitis.

Features of Our Center

Results of ESD by Dr. Yahagi at the University of Tokyo Hospital, Toranomon Hospital, and Keio University Hospital (2000-2010)

Esophageal ESD 452 lesions
Stomach ESD 1,564 lesions
Duodenal ESD 76 lesions
(Large Intestinal) ESD
677 lesions

In our hospital, the clinical departments work in close cooperation to treat diseases from a broad perspective. To develop our practice and provide cancer treatment for the full range of organs beyond the borders of clinical departments, the Tumor Center was established in 2009.

As a result, in the case of gastrointestinal cancers, for example, respective experts in each field work as a team to provide seamless medical services such as endoscopic treatment at a very early stage, laparoscopic treatment at somewhat advanced stages, and chemotherapy and radiation therapy at the stage of advanced cancer. We have a unique R&D department focusing on developing new techniques and devices for less invasive cancer treatments, and have already developed ground-breaking methods and equipment, while gaining much experience. We can perform less invasive operations regardless of the size and location of the cancer provided it has not spread to the lymph nodes. Dr. Naohisa Yahagi, department director, is renowned as one of the developers of ESD, with more than ten years of experience and achievements.

A Message to International Patients from Our Center

Dr. Yuko Kitagawa
Dr. Yuko Kitagawa
Director of the Center

Dr. Naohisa Yahagi
Dr. Naohisa Yahagi
Director of the Development and Research Department of Less Invasive Treatment Methods

For various tumors, from the very early stage to the advanced stage, our center will select the ideal treatment method for each patient and perform it expertly and safely. In particular, if a tumor is found at an early stage, we will perform a less invasive treatment to retain the organ. To detect cancer at an early stage, please undergo a screening endoscopic examination, and, if you have any doubts, please consult us immediately so that we can instruct you about the best treatment method. In particular, we developed the ESD treatment method ourselves, so we offer world-class expertise, techniques, and equipment.

Overview of the Treatment Schedule(Model Case: ESD of a Stomach Cancer)

Please send us endoscopic photographs and a histopathological report if possible before your admittance. If you do not have any of these, you can undergo examinations at our center after you come to Japan, but please note that depending on the condition of the cancer, we may be unable to assist you,

Overview of Treatment Schedule


External View of Our Hospital Treatment Rooms Patient Room (Suite)
External View of Our Center Example of Esophageal Cancer Treatment with ESD Laparoscopic Surgery
Hospital Contact Information
Phone (for international visitors):
+81-3-3353-1211 (Reception, English only)
2009 (Hospital established in 1920)
Clinical Departments
Chemotherapy Clinic, Radiation Oncology, Palliative Medicine, Development and Research Less Invasive Treatment Methods, Rehabilitation
Payment Methods
Cash, Debit Card (Hospitalization Payment Only),
Credit Card (JCB, DC, VISA. MasterCard, Diners Club)
35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582


Approximately 1 minute on foot from the JR Shinanomachi Station
Approximately 5 minutes on foot from Toei Subway
Kokuritsu-Kyogijo Station
Approximately 15 minutes on foot from Tokyo Metro
Yotsuya-Sanchome Station, and Toei Subway
Aoyama-ltchome Station
60 minutes from Tokyo International
Airport (Haneda Airport) by car
120 minutes from Narita International Airport by car