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National Center for Global Health and Medicine Hospital

Conditions Treated
Multiple Myeloma, Blood Disease as HIV Complication (Malignant Lymphoma in Particular).

Treatment Methods (Autologous Hematopoietic Stem Cell Transplantation by a Multidisciplinary Medical Team)

Among hematologic cancers, multiple myeloma is a disease from which complete recovery is still difficult. Treatment methods depend on the cancer stage and/or transition; for those under the age of 65, autologous hematopoietic stem cell transplantation is frequently performed. In this treatment method, a large amount of anticancer drugs is administered before the transplant. Therefore, mucosal injuries may occur in the oral cavity or alimentary canal as a side effect, which may make it impossible to take meals from the mouth, or a central venous feeding catheter or ulcer may cause infection, which are serious problems.

To mitigate these problems, since 2005 our hospital has been improving the overall care for patients undergoing hematopoietic stem cell transplantation managed by a multidisciplinary medical team consisting of doctors, nurses, dieticians, pharmacists, dentists, dental hygienists, and so forth. The nurses provide oral cryotherapy to suppress mucosal injuries and thus maintain oral feeding of nutrients, while the dentists and dental hygienists take care of the oral cavity to prevent infection. Meanwhile, dieticians assist with nutrition for the recovery of hematopoietic tissue. As a result, rehabilitation training is possible from an early stage, leading to an earlier return to daily life. These efforts have reduced complications associated with transplantation as well as reduced the hospitalization period and medical expenses, attracting attention from around the world. Since we introduced this method, the five-year survival rate after hematopoietic stem cell transplantation at our hospital is as high as 80 percent along with progress of chemotherapies for multiple myelomas. Few medical facilities in the world are able to provide such comprehensive, high-level support for hematopoietic stem cell transplantation.

Among the blood diseases seen as HIV complications, malignant lymphomas in particular do not respond well to chemotherapy and are seen as refractory; for such cases, hematopoietic stem cell transplantation is often effective. HIV patients often have weakened physical strength and/or immune strength, so the total care provided by our multidisciplinary medical team including nutrition support is especially effective.

Features of Our Hospital

Our hospital was founded as a national center promoting international medical cooperation in Japan. We have a wide range of medical departments and divisions such as the AIDS treatment/research and development center, the international diseases center, the international medical cooperation department, and so forth. These allow us to provide specialized, overall medical treatment for various types of patients who have underlying diseases.

We have already performed more than 260 hematopoietic stem cell transplants related to multiple myelomas, and our results are in the top class in Japan. We also cooperate with the Japanese branch of the International Myeloma Foundation to provide information to patients, thus making us a major medical facility in the field of multiple myeloma treatment.

Furthermore, we have performed more than 640 surgeries for HIV patients and have extensive experience with HIV treatment.

Results of Transplants for Myeloma
(1995 -2011)

Results of Transplants for Myeloma (1995 -2011)

Results of Transplants for
AIDS-related Lymphomas (1995 -2010)

Results of Transplants for AIDS-related Lymphomas (1995 -2010)

A Message to International Patients from Our Hospital

Our hospital, with its core mission of promoting international medical cooperation, provides highly advanced medical treatment through all of our facilities and departments. Japanese society is aging and so patients often have two or more diseases. This is why we have created a system so that every patient can receive cooperative medical treatment combining all departments and occupational categories, which we call “Total Team Therapy.” We make good use of this experience to assist our international patients. In addition, we have much experience in sending and receiving staff to and from overseas, and we have staff who can speak several languages, thus reducing anxiety for patients undergoing treatments. We have already accepted many international patients, and provide the latest treatments with an international perspective.

Dr. Sosuke Kimura
Dr. Sosuke Kimura
Medical Director

Dr. Akiyoshi Miwa
Dr. Akiyoshi Miwa
Manager of the Division of Advanced Care

Dr. Shotaro Hagiwara
Dr. Shotaro Hagiwara
Director of the Hematology Department

Other Clinical Departments at Our Hospital

In the field of the digestive organs, because doctors in our hospital are taking a leading role in developing new equipment and technologies, we can perform endoscopic surgery for stomach and large bowel cancers that are larger than could be treated with conventional methods. These high-quality cancer treatments are based on a multidisciplinary approach, with PET cancer examinations enabling advanced treatment. In addition to conventional PET scanning using glucose, we are one of the few facilities in Japan to use methionine, and the thiol-thymidine PET that we developed is available only at our hospital. This is extremely helpful in determining future treatment plans.

We also conduct world-class research and treatment in collaboration with the research center, including the development of treatment drugs based on the discovery of new disease-related enzymes in the field of rheumatism and oral surgery, and are studying treatment drugs and genes responsible for progressive condylar resorption, an incurable disease, in the field of oral surgery.


External View of Our Hospital Rehabilitation Equipment
External View of Our Hospital Rehabilitation Equipment (on the Advanced Medical Treatment Ward Floor)
Hospital Contact Information
Established 1993
(Founded as the National Center for Global Medical Treatment)
Clinical Departments
Internal Medicine, Respiratory Medicine, Cardiovascular Medicine, Diabetic Tract Medicine, Gastrointestinal Medicine, Hematology, Endocrine Metabolism, Nephrology, Neurology, Psychosomatic Medicine, Infectious Disease, Neonatology, Endoscope, Dialysis, Mitigating Care, Pain Clinic, Allergology, Rheumatism, Surgery, Respiratory Surgery, Cardiovascular Surgery, Digestive Surgery, Pediatric Surgery, Orthopedics, Neurosurgery, Plastic Surgery, Head and Neck Surgery, Psychiatry, Pediatrics, Dermatology, Urology, Obstetrics, Gynecology, Ophthalmology, Otorhinolaryngology, Rehabilitation, Radiation Clinic, Radiation Therapy, Dentistry, Dental Surgery, Anesthesiology, Diagnostic Pathology, Emergency
Payment Methods
Cash, Debit Card, Credit Card (Nicos, VISA, MasterCard)


1-21-1 Toyama, Shinjuku-ku, Tokyo 162-8655
5 minutes on foot from Toei Subway
Wakamatsukawada Station
15 minutes on foot from
Tokyo Metro Waseda Station
50 minutes from Tokyo International Airport
(Haneda Airport) by car
90 minutes from Narita International Airport
by car